Nevus of ota neelam n redkar1, kavita j rawat2, siddharth warrier 3, anurag jena4 n evus of ota noo also known as congenital melanosis bulbi, 1 nevus fuscoceruleus, ophthalmomaxillaris, oculodermal melanocytosis2 and oculomucodermal melanocytosis. Nevus of ota laser treatment washington, dc dermatologist. Mar 26, 2019 nevus of ota, which originally was described by ota and tanino in 1939, is a hamartoma of dermal melanocytes. Nevus of ota is a benign dermal melanocytic nevus that typically affects asian children and women. The nevi develop from melanocytes, which are the cells in the bottom layer of the epidermis, or the skins outer layer.
The first page of the pdf of this article appears above. This is a wellprepared case report of meningeal melanocytoma associated with nevus of ota. The condition, originally described by ota and tanino in 1939, mainly affects the ophthalmic and maxillary divisions of the trigeminal nerve. The nevus presents as unilateral bluegray hyperpigmented macules and patches scattered along the first and second divisions of the trigeminal nerve. Yag, qswitched ruby, qswitched alexandrite, or qswitched neodymiumyag lasers. Cerebellar meningeal melanocytoma associated with nevus of ota. The nevus is a particular disease of the japanese population, having been originally reported by ota in 1939. Nevus of ota is a dermal melanocytosis originally described by ota and tanino in 1939. Several retrospective studies described the recurrence rate after treatment is extremely low as 0. Nevus of ota no is a hamartoma of dermal melanocytes usually presents as unilateral blue, gray or brown macules or patches. Nevus of ota is referred to as nevi of ota in plural form. The first case of phakomatosis pigmentovascularis figure 6 was described in 1920 in a patient with.
Dendritic melanocytes are located in the reticular and papillary dermis with a normal overlying epidermis. Nevus of ota, or nevus fuscoceruleus ophthalmomaxillaris, is a discoloration of the skin and mucous membranes that occurs in the areas connected to the first two branches of the trigeminal nerve. You want to find a practice that uses the qswitched nd. Hyperpigmentation of parts of the eye may occur sclera. Nevus of ota, also known as congenital melanosis bulbi or oculodermal melaocytosis, is a skin condition affecting the upper third of the dermis. Nevus of ito is less common than nevus of ota, although the true incidence is unknown. Although extracutaneous complications and melanoma can occur, they are uncommon, and most patients with nevus of. The nevus of ota appears as increased pigmentation of one eye and its eyelids. Yag 1064 nm lasers have all been shown to effectively treat nevus of ota. Recurrence of nevus of ota after successful laser treatment ncbi. New jersey medical school, 185 south orange ave, newark, nj. Clinically, nevus of ota presents as a blue or gray patch on the face, which is congenital or acquired and is within the distribution of the ophthalmic and maxillary branches of. Nov 12, 2015 nevus of ota is a benign dermal melanocytic nevus that typically affects asian children and women. Nevus of ota, synonymously termed oculodermal melanosis, is an uncommon dermal melanosis most commonly seen at birth in children of japanese descent, though it can affect individuals of any age or ethnicity.
Very often, nevus of ota occurs unilaterally in blacks and oriental women 4. Nevus of ota nevus fuscocoeruleus ophthalmomaxillaris or ocular dermic melanocytosis is a clinical condition characterized by bluedark pigmentation, greenblue, violet, or tan spots in the eyes andor on the faces skin and lids. Sep 28, 2011 nevus of ito is a colored birth mark that is usually slatebrown or bluegray. It is successfully treated by using qswitched lasers. These types of birthmarks require multiple treatments spaced 46 weeks apart, and there is a risk of early or late recurrence of the. Nevus of ito is a colored birth mark that is usually slatebrown or bluegray. Neuroradiologic manifestation revealed a lesion in the left cerebellar hemisphere, the etiology of the presenting tumor apoplexy figure 1, cf. Nevus of ota aka oculodermal melanocytosis is a hyperpigmentation along the distribution of the ophthalmic and maxillary branches of trigeminal nerve.
Nevus of ota is a type of dermal melanocytosis excessive melanocytes in the tissues that causes the hyperpigmentation of an eye and the surrounding area. Nov 06, 2001 lasers have revolutionized the treatment of nevus of ota and other dermal melanocytoses. Women are nearly five times more likely to be affected than men. Nevus of ota or oculodermal melanocytosis is a rare congenital hamartoma of dermal melanocytes causing a bluegray. Naevus of ota, naevus of ito and naevus of hori are special melanocytic naevi that have a slatebrown or bluegrey colouring.
Are qswitched lasers for nevus of ota really effective in pigmented skin pdf. Successful treatment of a patient with multicolored nevus of ota. Nevus of ota is a blue hyperpigmentation that occurs on the face, most often appearing on the. Only 12 cases so far have been reported in english literature and it is rare in indian subcontinent. Mar 09, 2012 are qswitched lasers for nevus of ota really effective in pigmented skin. Clinically, nevus of ota is distributed along the ophthalmic and maxillary divisions of the trigeminal nerve and presents as a blue or gray patch on the face. Nevus of ota symptoms, diagnosis, treatments and causes. Nevus of ota is a dermal melanocytosis seen along the distribution of ophthalmic and maxillary divisions of the trigeminal nerve. The qswitched ruby 694 nm, qswitched alexandrite 755 nm, and qswitched nd. The eyelid is darkened, pigment can be observed on the white of the eye and that iris may be darker compared to the contralateral iris. Nevus of ota, portwine stain, anterior staphyloma, glaucoma. Nevus of ota with portwine stain a rare entity semantic scholar. Nevus of ota, which originally was described by ota and tanino in 1939, is a hamartoma of dermal melanocytes. Kabir sardana, shikha chugh, vijay garg department of dermatology, maulana azad medical college, delhi, india.
Nevus of ota associated with intracranial melanoma. Nevus of ota nevus fuscoceruleus ophthalmomaxillaris is a bluegray or brown irregular, often spotted skin discoloration located on the face in the distribution of the first and second branches of the trigeminal nerve i. Nevus of ota affects females approximately 5 times more often than males. Primary meningeal melanocytoma of the cerebellopontine. There is a known association between nevus of ota and melanomas involving the brain parenchyma andor the meninges.
Recurrence of nevus of ota after successful laser treatment. Are qswitched lasers for nevus of ota really effective in. Meningeal melanocytoma associated with ipsilateral nevus. Individuals with nevus of ota experience emotional and psychosocial distress related to cosmetic disfigurement and often look for treatment. We describe the first reported case of unilateral oculodermal melanocytosis. Visit our research pages for current research about nevus of ota treatments clinical trials for nevus of ota. The disease tends to persist and extend locally, becoming increasingly. Nevus of ota definition of nevus of ota by medical dictionary. Nevus of ota a rare pigmentation disorder with intraoral. Are qswitched lasers for nevus of ota really effective in pigmented skin. Article information, pdf download for oculodermal melanocytosis. Nevus of ota or oculodermal melanocytosis is a rare congenital.
Nevus of ota is a fairly common hyperpigmentary dis. The treatment options for this condition included cryotherapy, dermabrasion, surgical excision and cosmetic camouflage. In 1916, pusey described the case of a chinese student with both scleral and facial pigmentation. In 1956, fitzpatrick et al5 renamed the syndrome oculodermal melanocytosis. Nevus of ota definition of nevus of ota by medical. Nevus of ota nyc laser skin surgery center of new york. Aug 20, 2014 nevus of ota is a dermal melanocytosis seen along the distribution of ophthalmic and maxillary divisions of the trigeminal nerve.
Nevus of ota is an uncommon pigmentation on the skin, often arising at birth but sometimes arising in childhood or teenage years. It is an unusual birthmark in which the melanocytes pigment cells are found deeper than normal in the skin. Mar 02, 2018 nevus of ota is a type of dermal melanocytosis excessive melanocytes in the tissues that causes the hyperpigmentation of an eye and the surrounding area. Nevus of ota, also known as nevus fuscoceruleus opthalmomaxillaris, represents a benign partially confluent macular brownblue pigmentation of the skin and mucous membranes in the distribution of the first and second branches of the trigeminal nerve. Nevus of ota is a fairly common hyperpigmentary disorder in asians and usually appears at birth or in childhood. Although extracutaneous complications and melanoma can occur, they are uncommon, and most patients with nevus of ota suffer from the psychological. Nevus of ito genetic and rare diseases information center. Mar 14, 2020 home forums uk voice forum ota nevus pdf editor tagged. She had a congenital grayishblue pigmented nevus on her left side face, which involved ipsilateral sclera and oral mucosal membrane, diagnosed as nevus of ota figure 1, a and b. Nevi of ota and ito occur most frequently in individuals of asian descent, with an estimated prevalence of 0. Mar 22, 2020 nevus of ota is referred to as nevi of ota in plural form.
Recurrences generally develop at the previous site. Notably, the first published paper on the laser treatment of nevus of ota was written by dr. The author precisely described the clinical characteristics, pathological conditions, and biological findings of meningeal melanocytoma. We present the unusual case of a 32yearold africanamerican female with a nevus of ota and a contralateral parenchymal, primary cns melanoma. Meningeal melanocytoma associated with ipsilateral nevus of. Naevus of ota, naevus of ito and naevus of hori dermnet nz. Nevus of ota or oculodermal melanocytosis is a rare congenital hamartoma of dermal melanocytes causing a bluegray hyperpigmentation of the eye and surrounding structures. A 20yearold woman presented with a 2day history of headache.
Otas nevus definition of otas nevus by medical dictionary. Nevus of ota, also known as oculodermal melanocytosis or nevus fuscoceruleus ophthalmomaxillaris, is a hamartoma of dermal melanocytes that is characterized by a unilateral or bilateral bluebrown, speckled patch usually involving the malar, periorbital, temple, andor forehead regions of the face. They are forms of dermal melanocytosis in which naevus cells are found deep within the dermis. The nevus of ota is a misnomer because it does not contain true nevus cells and derives its pigmentation from dendritic melanocytes which are found in the reticular layer of the dermis. Clinically, nevus of ota presents as a blue or gray patch on the face, which is congenital or acquired and is within the distribution of the ophthalmic and maxillary branches of the trigeminal nerve. Mar 26, 2019 nevi of ota and ito occur most frequently in individuals of asian descent, with an estimated prevalence of 0. The nevus of ota also known as congenital melanosis bulbi and oculodermal melanocytosis is a bluegray hyperpigmentation that occurs on the face and eyes. Lasers have revolutionized the treatment of nevus of ota and other dermal melanocytoses.
Possible role of dermal stem cells hyun soo lee1, misun kim1,2, hee young kang1,2 departments of 1dermatology and 2biomedical science, ajou university school of medicine, suwon, korea dear editor. The sclera is involved in twothirds of cases causing an increased risk of glaucoma. This type of birthmark is usually located on the shoulder and upper arm area on one side of the body. Primary meningeal melanocytoma of the cerebellopontine angle. The ota nevus or nevus fuscocaeruleus ophthalmomaxillaris, originally described by ota in 1939, is a hyper melanocytosis of the periorbital region observed more frequently in subjects of asian origin and blacks. Shown here is a patient with nevus of ota prior to treatment. Pdf primary meningeal melanocytoma of the cerebellopontine. Nevus of ota oculodermal melanocytosis, nevus fuscoceruleus ophthalmomaxillaris is a dermal melanocytic hamartoma that presents as bluishslategray hyperpigmentation along the first or second branch of the trigeminal nerve. The co2 laser is not a good tool and whomever suggested that for you was wasting your time and money. Pdf are qswitched lasers for nevus of ota really effective. Nevus of ota is a dermal melanocytosis common among.
These lasers specifically target the pigment within the birthmark. Naevus of ota is on the forehead and face around the eye area. More accurately grouped with dermal melanocytoses nevus of ito, nevus of ota, hori nevus, socalled mongolian spot emedicine nevi of ota and ito although melanocytic, it is not a true nevus different entity from hypomelanosis of ito, a neurocutaneous disorder j child neurol 2000. Dear editor, laser therapy for ocular lesions of naevus of ota naevus of ota is a bluegray pigmentation of the sclera and adjacent skin caused by dermal melanocytes. The treatment of choice for nevus of ota is laser therapy. Patients with the nevus of ota should be examined at least every 6 months by an eyecancer specialist and a neurologist. Nevus of ota birthmarks can be treated using our picosecond nd. Nevus of ito genetic and rare diseases information. It also occurs on the forehead, nose, cheek, periorbital region, and temple. Keywords nevus of ota, melanocytes, glaucoma, melanocytosis, melanoma, dog. Its a dermal melanocytosis seen along the distribution of ophthalmic and. Pdf nevus of ota, a dermal melanocytic nevus, is rare in the indian subcontinent. Individuals with nevus of ota experience emotional and psychosocial distress related to cosmetic disfigurement and often look for treatment options. Ota, known by the pen name mokutaro kinoshita, was a japanese doctor who first described the condition in 1939, which is why it is named after him.
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